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20150703

Goblet cells are present in all except?

a. Small intestine
b. Large intestine
c. Esophagus
d. Stomach

Goblet cells: glandular simple columnar epithelial cells.

     - secretes mucin, which dissolves in water to form mucus.
     - use apocrine and merocrine methods.
     - found in epithelial lining of intestinal and respiratory tracts.

: Trachea, bronchus, bronchioles
: Small intestine, Colon
: Conjunctiva in upper eyelid




Clinical significance
Goblet cell carcinoids are a class of rare tumors that form as a result of an excessive proliferation of both goblet and neuroendocrine cells. The majority of these tumors arise in the appendix and may present symptoms similar to the much more common acute appendicitis.The main treatment for localized goblet cells tumors is removal of the appendix, and sometimes removal of the right hemicolon is also performed.Disseminated tumors may require treatment with chemotherapy in addition to surgery.

Goblet cells may be an indication of metaplasia, such as in Barrett's esophagus.



Ans d. Stomach

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