Sign or Symptom | Peripheral (Labyrinth or Vestibular Nerve) | Central (Brainstem or Cerebellum) |
---|---|---|
Direction of associated nystagmus | Unidirectional; fast phase opposite lesiona | Bidirectional (direction-changing) or unidirectional |
Purely horizontal nystagmus without torsional component | Uncommon | May be present |
Purely vertical or purely torsional nystagmus | Never presentb | May be present |
Visual fixation | Inhibits nystagmus | No inhibition |
Tinnitus and/or deafness | Often present | Usually absent |
Associated central nervous system abnormalities | None | Extremely common (e.g., diplopia, hiccups, cranial neuropathies, dysarthria) |
Common causes | Benign paroxysmal positional vertigo, infection (labyrinthitis), vestibular neuritis, Ménière's disease, labyrinthine ischemia, trauma, toxin | Vascular, demyelinating, neoplasm |
a In Ménière's disease, the direction of the fast phase is variable.
b Combined vertical-torsional nystagmus suggests BPPV.
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