Classification for Lupus Nephritis

Class I	Minimal mesangial	Normal histology with mesangial deposits
Class II	Mesangial proliferation	Mesangial hypercellularity with expansion of the mesangial matrix
Class III	Focal nephritis	Focal endocapillary ± extracapillary proliferation with focal subendothelial immune deposits and mild mesangial expansion
Class IV	Diffuse nephritis	Diffuse endocapillary ± extracapillary proliferation with diffuse subendothelial immune deposits and mesangial alterations
Class V	Membranous nephritis	Thickened basement membranes with diffuse subepithelial immune deposits; may occur with Class III or IV lesions and is sometimes called mixed membranous and proliferative nephritis
Class VI	Sclerotic nephritis	Global sclerosis of nearly all glomerular capillaries