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Dear Medicos,
This site contains a comprehensive list of medical PG entrance questions asked in various PG entrance examination throughout India like AIIMS, AIPGEE, PGI CHANDIGARH, JIPMER, CMC VELLORE .... and various state entrance exams like KERALA, TAMIL NADU, KARNATAKA, DELHI .... and also private entrances like COMEDK, MANIPAL etc...
A young boy presents with failure to thrive. Biochemical analysis of a duodenal aspirate after a meal reveals a deficiency of enteropeptidase. The levels of the foll digestive enzyme would be affected:
a. Amylase.
b. Pepsin.
c. Lactose.
d. Trypsin.
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DIAGNOSIS: Enterokinase deficiency: The presentation is of infants that are ill from very early in life with severe diarrhoea and failure to thrive. Hypoproteinaemia is common in this condition and this may cause oedema. The tryptic activity in duodenal juice is missing while lipase and amylase are normal. In vitro the activity of the juice can be restored by the addition of enterokinase. The major result of this condition is malabsorption of protein although steatorrhoea has been reported.
The supplementation of the diet with pancreatic enzyme replacements restores normal digestive function.
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D. Trypsin.
DIAGNOSIS: Enterokinase deficiency:
The presentation is of infants that are ill from very early in life with severe diarrhoea and failure to thrive. Hypoproteinaemia is common in this condition and this may cause oedema. The tryptic activity in duodenal juice is missing while lipase and amylase are normal. In vitro the activity of the juice can be restored by the addition of enterokinase. The major result of this condition is malabsorption of protein although steatorrhoea has been reported.
The supplementation of the diet with pancreatic enzyme replacements restores normal digestive function.
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