Guide to NSAID Therapy

No/Low NSAID GI Risk NSAID GI Risk No CV risk (no aspirin) Traditional NSAID Coxib or      Traditional NSAID + PPI or misoprostol     Consider non-NSAID therapy CV risk (consider aspirin) Traditional NSAID + PPI or misoprostol if GI risk warrants gastroprotection A gastroprotective agent must be added if a traditional NSAID is prescribed   Consider non-NSAID therapy Consider non-NSAID therapy