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20110519

Which one of the following statements about Hemoglobin S is not true:



  1. HbS differs from HbA by the substitution of Val for Glu in position 6 of the beta chain.
  2. One altered peptide of HbS migrates faster towards the cathode than the corresponding peptide of HbA.
  3. Binding of HbS to the deoxygenated HbA can extend the polymer and cause sickling of the red blood cells.
  4. Lowering the concentration of deoxygenated HbS can prevent sickling.

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1 comment:

lejako said...

3. Binding of HbS to the deoxygenated HbA can extend the polymer and cause sickling of the RBC.


HbA, HbC and HbF afford protective affect from sickling.

21.5.11

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