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The HLA clas III region genes are important elements in :

  1. Transplant rejection phenomenon.
  2. Governing susceptibility to autoimmune diseases.
  3. Immune surveillance .
  4. Antigen presentation and elimination.
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1 comment:

lejako said...

2. Governing susceptibility to autoimmune disease.

Class III codes for early complement components (c2, c4), deficiency of which leads to SLE and other autoimmune diseases.

3.5.11

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