AIIMS NOV 2011 (direct repeats)

AIIMS NOVEMBER 2011 – Review by PGQB team.

 Ref: Review of AIIMS by Ashish Gupta, Amit Tripathi

         AIPGMEE Review by Mudit Khanna.

ANATOMY

PHYSIOLOGY

12. Adrenaline, noradernaline and dopamine act through:

(AIIMS Nov 2006)

a. Single pass receptor

b. Four pass receptor

c. Seven pass receptor

d. Ligand gated receptor

14. Mean arterial pressure is calculated as:

(AIIMS Nov 2006)

a. (SBP + 2DBP)/3

b. (DBP + 2SBP)/3

c. (SBP + 3DBP)/2

d. (DPB + 3SBP)/2

BIOCHEMISTRY

20. Same amino acid is coded by multiple codons due to following:

(AIIMS Nov 2006)

a. Degeneracy

b. Frame-shift mutation

c. Transcription

d. Mutation

23.  Anticoagulant used to estimate glucose from a sample sent from PHC is

(AIIMS Nov 2006)

a. EDTA

b. Calcium oxalate

c. Potassium oxalate + NaF

d. Sodium citrate

25. The 40 nm gap between the tropocollagen molecule in collagen, which serve as the site of bone formation is occupied by which of the following:

(AIIMS Nov 2006)

a. Carbohydrate

b. Ligand moeity

c. Ca++

d. Fe ++

30. All of the following are true regarding oxygenases except:

(AIPGMEE 2007)

a. Incorporate 2 atoms of oxygen.

b. Incorporate 1 atom of oxygen.

c. Required for hydroxylation of steroids.

d. Required for carboxylation of drugs.

40. CAP in LAC operon is an example of:

(AIPGMEE 2007)

a. Positive regulator

b. Negative regulator

c. Constitutive expression

d. Attenuation.

23. Poly (A) tail translates into:

(AIIMS May 2008)

a. Poly proline

b. Poly lysine

c. Poly alanine

d. Poly glycine.

FORENSIC MEDICINE

COMMUNITY MEDICINE

39. You have diagnosed a patient clinically as having SLE and ordered 6 tests. Out of which 4 tests have come positive and 2 are negative. To determine the probability of SLE at this point, you need to know:

(AIIMS Nov 2006)

a. Prior probability of SLE; sensitivity and specificity of each test.

b. Incidence of SLE and predictive value of each test.

c. Incidence and prevalence of SLE.

d. Relative risk of SLE in this patient.

41. Direct standardization is used to compare the mortality rates between two countries. This is done because of the difference in:

(AIIMS Nov 2006)

a. Causes of death.

b. Denominators

c. Age distributions

d. Numerators.

45. Using a new technique, Hb was estimated in a blood sample.  The test was repeated 10 times.  The reports were :  9.5, 9.2, 9.4, 9.6, 9.7, 9.9, 10.2, 10.3, 10.5, 12.1. Accurate value of Hb was estimated by standard tests to be 10.2. The new technique has:

(AIIMS Nov 2006)

a. High validity and high reliability

b. Low validity and low reliability

c. High validity and low relibility

d. Low validity and high reliability.

46. In a study in UK, an association was found between sale of antiarrhytmic drug and an increase in deaths due to asthma. This is an example of

(AIIMS Nov 2006)

a. Ecological study

b. Cohort study

c. Case reference study

d. Experimental study.

49. Socialization of medicine leads to all except:

(AIIMS Nov 2006)

a. Ensures complete utilization of services by all people.

b. Free medical care supported by state.

c. Eliminates the competition among physicians in search of clients.

d. Ensures social equity, universal coverage of health services.

56. Which epidemiological study gives the most accurate result:

(AIIMS Nov 2006)

a. Meta analysis.

b. Cross-sectional study.

c. Randomized control trial with double blind.

d. Cohort study.

49. Best method to compare new test and gold standard test:

(AIIMS May 2007)

a. Correlation study

b. Regressive study

c. Bland and Altman analysis

d. Kolmogorov- Smirnov test

PHARMACOLOGY

72. The following drug is not useful for MRSA.

(AIIMS Nov 2006)

a. Cefaclor

b. Cotrimoxazole

c. Ciprofloxacin

d. Vancomycin

86. True about Octreotide are all­ except:

(AIPGMEE 2007)

a. Is active orally.

b. Supresses growth hormone secretion

c. Useful for variceal bleeding

d. Useful in secretory diarrhea.

MICROBIOLOGY

74. An elderly male presented with fever, chest pain and dry coug.  Sputum cultured on charcoal yeast medium.  The organism is :

(AIIMS Nov 2006)

a. H.influenza

b. Moraxella catarrhalis

c. Legionella

d. Burkholderia cepacia

76. A young male presented with urethral discharge.  On urine examination, pus cells were found but no organisms. Which method would be the best for culture?

(AIIMS Nov 2006)

a. Mc coy cell line

b. Thayer Martin medium

c. LJ medium

d. Levinthal medium

80. With reference to Bacteroides fragilis, the following statements are true except:

(AIIMS Nov 2006)

a. B. fragilis is the same frequent anaerobe isolated from clinical samples.

b. B. fragilis is not uniformly sensitive to metronidazole.

c. The lipopolysachharide formed by B. fragilis is structurally and functionally different from the conventional endotoxin.

d. Shock and DIC are common in Bacteroides bacteremia.

81. A child had pustular lesion on leg. On gram staining, gram positive coccin are seen . To establish the diagnosis of Group A streptococcal erythroderma, the test used is :

(AIIMS Nov 2006)

a. Bile solubility test

b. Catalase test

c. Optochin sensitivity

d. Bacitracin sensitivity

82. A patient admitted to an ICU is on central venous line for last one week.  He is on ceftazidime and amikacin.  After 7 days of antibiotics, he develops a spike of fever and his blood culture is positive fro gram positive cocci in chains, which are catalase negative.  Following this, vancomycin was started but the culture remained positive for the same organism, even after 2 weeks of therapy.  The most likely organism causing infection is:

(AIIMS Nov 2006)

a. Staphylococcus aureus

b. Viridans streptococci

c. Enterococcus faecalis

d. Coagulase negative staphylococci.

67. In plasma sterilization, control used is:

(AIIMS Nov 2010)

a. B. subtilis

b. B. steatothermophilus

c. C. perfringens

d. C. tetani.

PATHOLOGY

93. In acute inflammation due to the contraction of endothelial cell cytoskeleton, whicn of the following results:

(AIIMS Nov 2006)

a. Delayed transient increase in permeability

b. Early transient increase

c. Delayed permanent increase

d. Early permanent increase

95. The most common gene defect in idiopathic steroid resistant nephrotic syndrome:

(AIIMS Nov 2006)

a. ACE

b. NPHS 2

c. HOX 11

d. PAX

MEDICINE

98. Reflux disease, which cause of proteinuria is nephrotic range?

(AIIMS Nov 2006)

a. Membranous glomerulonephritis

b. Focal segmental glomerulosclerosis

c. Nodular glomerulosclerosis

d. Crescenteric glomerulonephritis.

99. Which deleterious effect is least likely to occur in hypothermia?

(AIIMS Nov 2006)

a. Cardiac arrhythmia

b. Decreased peripheral resistance

c. Reversible coagulation

d. Renal failure.

104. Treatment for multiple sclerosis:

(AIIMS Nov 2006)

a. Interferon alpha

b. Interferon beta

c. Infliximab

d. Interferon gamma.

108. Which of the following is not a limb girdle dystrophy?

(AIIMS Nov 2006)

a. Sarcoglycan dystrophy

b. Dystrophin dystrophy

c. Dysferin dystrophy

d. Calpain dystrophy.

109. Which of the following is the most specific test for Rheumatoid arthritis?

(AIIMS Nov 2006)

a. Anti-ccp antibody

b. Anti Igm antibody

c. Anti IgA antibody

d. Anti IgG antibody

112. Which of the following exclusively involve neurons?

(AIIMS Nov 2006)

a. Spinocerebellar ataxia

b. Supranuclear palsy

c. Corticobasilar degeneration

d. Multiple system atrophy.

114. A young male patient presents with LDL 600 mg/dl, triglycerides 160 mg/dl.  What would be the most likely finding on physical examination?

(AIIMS Nov 2006)

a. Tendon xanthoma.

b. Lipemia retinalis

c. Eruptive tuberous xanthoma

d. Xanthelasma.

119. HAM test is done for:

(AIIMS Nov 2006)

a. GPI anchor protein

b. Complement defect

c. Spectrin defect

d. Mannose binding protein.

175. The following are components of Brown Sequard syndrome except:

(AIPGMEE 2007)

a. Ipsilateral extensor plantar response.

b. Ipsilateral pyramidal tract involvement.

c. Contralateral spinothalamic tract involvement.

d. Contralateral posterior column involvement.

176. Which of the following is the classical CSF finding seen in TBM?

(AIPGMEE 2007)

a. Increased protein, decreased sugar, increased lymphoctes.

b. Increased protein, sugar and lymphocytes.

c. Decreased protein, increased sugar and lymphocytes.

d. Increased sugar, protein and neutrophils.

PEDIATRICS

121. A newborn presents with congestive heart failure, on examination has bulging anterior fontanellae with a bruit on auscultation.  Trans fontanella USG shows a hypoechoic midline mass with dilated lateral ventricles.  Most likely diagnosis is:

(AIIMS Nov 2006)

a. Medulloblastoma.

b. Encephalocele

c. Vein of Galen malformation

d. Arachnoid cyst.

123. All the following can occur in a neonate for heat production except:

(AIIMS Nov 2006)

a. Shivering

b. Breakdown of brown fat with adrenaline secretion

c. Universal flexion like a fetus

d. Cutaneous vasoconstriction.

127. The most important fatty acid present in breast milk for growth is:

(AIIMS Nov 2006)

a. Docosahexaenoic acid

b. Palmitic acid

c. Linoleic acid.

d. Linolenic acid.

119. Kawasaki disease- treatment of choice:

(AIIMS May 2009)

a. ivIg

b. Steroid

c. Azathioprine

d. Antibiotics.

SURGERY

144. Which fruit juice helps in preventing UTI:

(AIIMS Nov 2006)

a. Grape

b. Raspberry

c. Cranberry

d. Orange

149. Which is not elevated in a child presenting with icterus, pruritus and clay coloured stools.

(AIIMS Nov 2006)

a. Gamma glutamyl transpeptidase

b. Alkaline phosphatase

c. 5- nucleotidase

d. Glutamate dehydrogenase.

151. A 45-yr old female complaints of progressive lower limb weakness, spasticity, urinary hesitancy.  MRI shows intradural enhancing mass lesion.  Most likely diagnosis is:

(AIIMS Nov 2006)

a. Dermoid cyst

b. Intradural lipoma

c. Neuroepithelial cyst

d. Meningioma.

154. Severity of acute pancreatitis correlate with levels of all of the following except:

(AIIMS May 2007)

a. Glucose

b. Amylase

c. Transaminase

d. Calcium.

ORTHOPAEDICS

249. Which is not a deep heat therapy?

(AIPGMEE 2007)

a. Short wave diathermy

b. Infrared therapy

c. Ultrasound therapy

d. Interferential therapy.

260. Which is not a marker of new bone formation?

(AIPGMEE 2007)

a. Alkaline phosphatase.

b. Osteocalcin

c. Urine Hydroxy proline

d. Pro collagen

262. Which of these muscles undergo wasting first in osteoarthritis knee?

(AIPGMEE 2007)

a. Quadriceps only

b. Hamstrings only

c. Both quadriceps and hamstrings

d. Gastronemius.

152. Gallow's traction is used for fracture:

(AIIMS Nov 2010)

a. Shaft femur.

b. Neck femur

c. Shaft tibia

d. Tibial tuberosity.

OBSTETRICS & GYNAECOLOGY

162. Which drug is given to prevent HIV transmission from mother to child?

(AIIMS Nov 2006)

a. Nevirapine

b. Lamivudine

c. Stavudine

d. Abacavir

163. After coming head of breech will have difficulty in delivery in all the following conditions except:

(AIIMS Nov 2006)

a. Hydrocephalus

b. Placenta previa

c. Incomplete dilation of cervix

d. Extension of head.

166. Lady with infertility with b/l tubal block at cornua.  Best method of managment:

(AIIMS Nov 2006)

a. Laparoscopy and Hysteroscopy

b. Hydrotubation

c. IVF

d. Tuboplasty

172. Which of the following is the least likely physiological change in pregnancy?

(AIIMS Nov 2006)

a. Increase in intravascular volume

b. Increase in cardiac output

c. Increase in stroke volume

d. Increase in peripheral vascular resistance.

174. Premature baby of 34 weeks was delivered. Baby had bullous lesion on the body.  X-ray shows periostitis.  What is the next investigation?

(AIIMS Nov 2006)

a. VDRL for mother and baby

b. ELISA for HIV

c. PCR for TB

d. Hepatitis surface antigen for mother.

120. 16 year old with primary amenorrhea attends OPD. She has normal sexual development and normal breast but with absent pubic and axillary hair.  Examination shows b/l inguinal hernias.  USG shows absent uterus and blind vagina.  Diagnosis will be:

(AIIMS Nov 2006)

a. Turner syndrome

b. Mullerian agenesis

c. STAR syndrome

d. Androgen insensitivity syndrome.

162. Marker for granulosa cell tumor:

(AIIMS May 2008)

a. CA 19-9

b. CA 50

c. Inhibin

d. Teratoma.

OPHTHALMOLOGY

180.  Oculomotor nerve palsy causes all except:

(AIIMS Nov 2006)

a. Miosis

b. Ptosis

c. Outward eye deviation

d. Diplopia.

ENT

SKIN

187. A 3 year old child has eczematous dermatitis on extensor surfaces. His mother has a history of bronchial asthma.  Diagnosis should be:

(AIIMS Nov 2006)

a. Atopic dermatitis

b. Contact dermatitis

c. Seborrheic dermatitis

d. Infantile eczematous dermatitis

177. Which of the following shows deposition of IgA in dermal papilla?

(AIIMS May 2009)

a. Dermatitis herpetiformis

b. IgA papillomatosis of childhood

c. Bullous pemphigoid

d. Gestational herpes.

178. Intraepidermal Ig G deposition is seen in:

(AIIMS May 2009)

a. Pemphigus

b. Bullous pemphigoid

c. Herpes genitalis

d. Dermatitis herpetiformis.

ANAESTHESIA

188. Which of the following is not true of Xenon anaesthesia?

(AIIMS Nov 2006)

a. Non explosive

b. Mnimal CVS side effect

c. Slow induction and recovery

d. Low blood gas solubility

189. Which of the following anaesthesia will produce decreased EEG activities?

(AIIMS Nov 2006)

a. Hypothermia

b. Early hypoxia

c. Ketamine

d. N2O

RADIOLOGY

PSYCHIATRY

PS: Rest of the questions to be updated once authenticated answers received.