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Features of Peripheral and Central Vertigo



Sign or SymptomPeripheral (Labyrinth or Vestibular Nerve)Central (Brainstem or Cerebellum)
Direction of associated nystagmusUnidirectional; fast phase opposite lesiona
 
Bidirectional (direction-changing) or unidirectional
Purely horizontal nystagmus without torsional componentUncommonMay be present
Purely vertical or purely torsional nystagmusNever presentb
 
May be present
Visual fixationInhibits nystagmusNo inhibition
Tinnitus and/or deafnessOften presentUsually absent
Associated central nervous system abnormalitiesNoneExtremely common (e.g., diplopia, hiccups, cranial neuropathies, dysarthria)
Common causesBenign paroxysmal positional vertigo, infection (labyrinthitis), vestibular neuritis, Ménière's disease, labyrinthine ischemia, trauma, toxinVascular, demyelinating, neoplasm


a In Ménière's disease, the direction of the fast phase is variable.
b Combined vertical-torsional nystagmus suggests BPPV.

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